Description

[1R,9Ar,(-)]-Octahydro-2H-Quinolizine-1-Methanol Acrylate is a specialized chiral acrylate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with high precision. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates, especially in alkaloid chemistry and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in developing advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis: Acts as a ligand precursor or a chiral auxiliary in catalytic processes to induce enantioselectivity.
• Fine Chemical Synthesis: Building block for creating specialty chemicals, flavors, and fragrances requiring defined three-dimensional structures.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies in organic and medicinal chemistry.
• Material Science: Potential monomer for creating specialized polymers with unique optical or mechanical properties derived from its quinolizine core.

Basic Information

Item	Detail
Product Name	[1R,9Ar,(-)]-Octahydro-2H-Quinolizine-1-Methanol Acrylate
CAS No.	60537-74-8
Molecular Formula	C14H23NO2
Molecular Weight	237.34 g/mol
Synonyms	(-)-Octahydro-2H-quinolizine-1-methanol acrylate; (1R,9aR)-Octahydro-2H-quinolizine-1-methanol acrylate; (1R,9aR)-1-(Hydroxymethyl)octahydro-2H-quinolizine acrylate ester; Acrylic acid (1R,9aR)-octahydro-2H-quinolizine-1-ylmethyl ester; Chiral quinolizine acrylate; 1-(Acryloyloxymethyl)octahydro-2H-quinolizine (enantiomer)
EINECS	Contact for details

Quality Control

Our [1R,9Ar,(-)]-Octahydro-2H-Quinolizine-1-Methanol Acrylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.