Description

2-Iodophenylhydrazine Hydrochloride is a versatile halogenated arylhydrazine salt that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive hydrazine moiety adjacent to an iodine substituent, enabling sequential functionalization for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of indole, indazole, and other nitrogen-containing heterocycles with potential biological activity.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its reactive sites for structural diversification.
• Dyestuff and Pigment Chemistry: Serves as a building block for creating complex azo dyes and colorants with specific light-fastness properties.
• Material Science: Employed in the preparation of functionalized polymers and ligands for catalytic systems.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and cyclization reactions due to the presence of both iodine and hydrazine functional groups.
• Analytical Reagent: Can be used in derivatization protocols for the detection and quantification of carbonyl compounds via hydrazone formation.

Basic Information

Item	Details
Product Name	2-Iodophenylhydrazine Hydrochloride
CAS No.	60481-34-7
Molecular Formula	C6H7IN2·HCl
Molecular Weight	270.50 g/mol
Synonyms	(2-Iodophenyl)hydrazine hydrochloride; 1-(2-Iodophenyl)hydrazine hydrochloride; o-Iodophenylhydrazine hydrochloride; 2-Iodo-phenylhydrazine HCl; Hydrazine, (2-iodophenyl)-, hydrochloride; 60481-34-7; (2-Iodophenyl)hydrazinium chloride
EINECS	Contact for details

Quality Control

Our 2-Iodophenylhydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white or light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.