Description

(2R)-2-(1-Hydroxy-1-Methylethyl)-5-Methyl-2,3,4,5-Tetrahydrofuro[3,2-C]Quinoline-4-One is a high-purity, chiral organic compound belonging to the tetrahydrofuroquinoline class, serving as a critical advanced pharmaceutical intermediate. Its defined stereochemistry and complex fused-ring structure make it an essential building block for the synthesis of novel, biologically active molecules. This compound is primarily required by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the production of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed in chiral pool synthesis or as a starting material for generating enantiomerically pure compounds due to its defined (2R) configuration.
• Fine Chemical Production: Serves as a specialized intermediate in the multi-step synthesis of complex, high-value organic molecules for various applications.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical manufacturing processes.

Basic Information

Product Name	(2R)-2-(1-Hydroxy-1-Methylethyl)-5-Methyl-2,3,4,5-Tetrahydrofuro[3,2-C]Quinoline-4-One
CAS No.	60354-62-3
Molecular Formula	C16H19NO3
Molecular Weight	273.33 g/mol
Synonyms	(2R)-2-(1-Hydroxy-1-methylethyl)-5-methyl-2,3,4,5-tetrahydrofuro[3,2-c]quinolin-4-one; (R)-2-(1-Hydroxy-1-methylethyl)-5-methyl-2,3,4,5-tetrahydrofuro[3,2-c]quinolin-4-one; 5-Methyl-2,3,4,5-tetrahydrofuro[3,2-c]quinolin-4-one, 2-(1-hydroxy-1-methylethyl)-, (2R)-; Tetrahydrofuro[3,2-c]quinoline derivative; Chiral furoquinoline intermediate
EINECS	Contact for details

Quality Control

Our production of (2R)-2-(1-Hydroxy-1-Methylethyl)-5-Methyl-2,3,4,5-Tetrahydrofuro[3,2-C]Quinoline-4-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.