Description

Benzo(A)Pyrenyl-9-Glucuronide is a crucial metabolite and analytical standard used for the detection and quantification of benzo[a]pyrene exposure. This compound is essential for high-precision research and regulatory compliance testing in environmental and biological monitoring. It is primarily utilized by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in toxicology studies and biomarker analysis.

Application

• Biomarker Analysis: Used as a primary analytical standard for quantifying benzo[a]pyrene metabolites in urine and serum for human biomonitoring studies.
• Toxicology Research: Serves as a critical reference material in metabolic pathway studies to understand the detoxification and bioactivation of polycyclic aromatic hydrocarbons (PAHs).
• Environmental Monitoring: Employed in method development and validation for assessing PAH exposure in occupational and environmental health studies.
• Pharmaceutical R&D: Used in drug metabolism and pharmacokinetics (DMPK) studies to investigate glucuronidation pathways and enzyme activity.
• Quality Control Reference: Acts as a certified reference material (CRM) for calibrating analytical instrumentation like HPLC-MS and GC-MS in testing laboratories.
• Regulatory Compliance Testing: Essential for assays supporting regulatory submissions to agencies like the EPA and FDA concerning carcinogen exposure limits.

Basic Information

Product Name	Benzo(A)Pyrenyl-9-Glucuronide
CAS No.	60262-87-5
Molecular Formula	C26H24O8
Molecular Weight	464.47 g/mol
Synonyms	Benzo[a]pyren-9-yl β-D-glucopyranosiduronic acid; 9-Hydroxybenzo[a]pyrene glucuronide; BP-9-Glucuronide; Benzo(a)pyrene-9-glucuronide; 9-BP-Gluc; B[a]P-9-Gluc; 9-Hydroxy-BaP glucuronide; 9-Benzo[a]pyrenyl glucosiduronic acid
EINECS	Contact for details

Quality Control

Our Benzo(A)Pyrenyl-9-Glucuronide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive analytical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods, and impurity profiles. We adhere to relevant industry standards for reference materials to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.