Description

Benzo(A)Pyrenyl-6-Glucuronide is a crucial metabolite and analytical standard used for the precise detection and quantification of benzo[a]pyrene exposure. This compound matters as a definitive biomarker in environmental and biological monitoring, enabling accurate risk assessment of polycyclic aromatic hydrocarbon (PAH) contamination. It is primarily needed by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in toxicology studies, metabolic research, and regulatory compliance testing for food, environmental, and occupational safety.

Application

• Biomarker Standard for PAH Exposure Studies: Serves as a primary reference standard in LC-MS/MS and HPLC analyses to quantify human or animal exposure to benzo[a]pyrene.
• Toxicology and Metabolic Pathway Research: Used to study the Phase II conjugation (glucuronidation) metabolic pathways of carcinogenic PAHs.
• Environmental Monitoring and Food Safety Testing: Essential for calibrating equipment and validating methods in labs testing for PAH residues in soil, water, air, and food products like smoked meats and oils.
• Occupational Health and Safety Compliance: Employed in assays to monitor worker exposure in industries such as aluminum production, coke ovens, and firefighting.
• Pharmaceutical Reference Material: Acts as a critical quality control component in the development of diagnostic kits and assays for carcinogen detection.
• Academic and Government Research: Utilized in universities and regulatory bodies (e.g., EPA, EFSA) for fundamental research on carcinogenesis and environmental persistence of pollutants.

Basic Information

Product Name	Benzo(A)Pyrenyl-6-Glucuronide
CAS No.	60262-85-3
Molecular Formula	C26H24O8
Molecular Weight	464.47 g/mol
Synonyms	Benzo[a]pyren-6-yl β-D-Glucopyranosiduronic Acid; 6-Hydroxybenzo[a]pyrene Glucuronide; BP-6-Glucuronide; B[a]P-6-Gluc; Benzo(a)pyrene-6-glucuronide; 3-[(1-Oxobenzo[a]pyren-6-yl)oxy]-β-D-glucopyranuronic acid; Benzo[a]pyrene 6-O-β-D-glucuronide
EINECS	Contact for details

Quality Control

Our Benzo(A)Pyrenyl-6-Glucuronide is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive analytical applications. Each lot undergoes rigorous testing via HPLC and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.