Description

Benzo(A)Pyrene-3-o-Glucuronide is a crucial conjugated metabolite of the potent environmental carcinogen Benzo(a)pyrene. This compound is of significant value for researchers and analytical laboratories focused on toxicology, metabolism, and biomarker studies. It serves as a vital reference standard and analytical tool for industries and institutions involved in environmental monitoring, pharmaceutical development, and occupational health and safety.

Application

• Biomarker Analysis & Metabolite Profiling: Used as a certified reference standard in HPLC, LC-MS, and GC-MS methods to quantify human exposure to polycyclic aromatic hydrocarbons (PAHs).
• Toxicology & Metabolic Pathway Research: Essential for studying the Phase II detoxification (glucuronidation) pathways of Benzo(a)pyrene in biological systems.
• Environmental & Occupational Health Monitoring: Critical for developing and validating assays to monitor PAH exposure in industrial settings, air pollution studies, and for workers in high-risk sectors.
• Pharmaceutical & Drug Metabolism Studies (DMPK): Employed in drug discovery to understand drug-drug interactions and the metabolic fate of xenobiotics.
• Food Safety & Contaminant Testing: Used in laboratories to calibrate equipment and validate methods for detecting PAH residues in food products, especially grilled or smoked foods.
• Regulatory Compliance & Method Development: Supports compliance testing for agencies like the EPA and FDA, ensuring analytical methods meet stringent quality standards.

Basic Information

Product Name	Benzo(A)Pyrene-3-o-Glucuronide
CAS No.	60262-81-9
Molecular Formula	C26H24O8
Molecular Weight	464.47 g/mol
Synonyms	Benzo[a]pyrene-3-yl β-D-glucopyranosiduronic acid; 3-Hydroxybenzo[a]pyrene glucuronide; BaP-3-O-glucuronide; 3-OH-BaP-Gluc; Benzo(a)pyrene 3-glucuronide; BP-3-G; 3-Hydroxybenzo(a)pyrene O-β-D-glucuronide
EINECS	Contact for details

Quality Control

Our Benzo(A)Pyrene-3-o-Glucuronide is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with relevant pharmacopeial and ISO guidelines for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. The product is light-sensitive and should be stored away from light. Keep the container sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.