Description

5-Chloro-2-Fluoro-3-Nitropyridine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated and nitrated pyridine core makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Used in the creation of specialized ligands, functionalized polymers, and advanced organic electronic materials.
• Chemical Biology: Serves as a versatile scaffold for probe and linker molecule development in drug discovery programs.
• Custom Synthesis: Fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) performing bespoke chemical synthesis.

Basic Information

Product Name	5-Chloro-2-Fluoro-3-Nitropyridine
CAS No.	60186-16-5
Molecular Formula	C5H2ClFN2O2
Molecular Weight	176.53 g/mol
Synonyms	3-Nitro-5-chloro-2-fluoropyridine; 2-Fluoro-5-chloro-3-nitropyridine; 5-Chloro-2-fluoro-3-nitro-pyridine; Pyridine, 5-chloro-2-fluoro-3-nitro-; 60186-16-5
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.