Description

2-Nitro-5-Azidobenzoic Acid is a specialized aromatic compound that serves as a versatile bifunctional building block in advanced organic synthesis. Its unique structure, featuring both nitro and azido functional groups on a benzoic acid core, makes it a valuable precursor for click chemistry, photoaffinity labeling, and the synthesis of heterocyclic compounds. This chemical is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and materials science.

Application

• Click Chemistry Reagent: Acts as a key precursor for Huisgen 1,3-dipolar cycloaddition reactions, facilitating the synthesis of complex triazole-linked molecules for drug discovery and bioconjugation.
• Photoaffinity Labeling (PAL): The azido group can generate nitrenes upon photolysis, enabling the covalent tagging and study of biological targets, protein-ligand interactions, and active sites.
• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs, particularly those requiring nitro-aromatic or heterocyclic scaffolds.
• Agrochemical Research: Employed in developing new herbicides, fungicides, and insecticides by incorporating its aromatic nitroazide functionality.
• Polymer and Materials Science: Serves as a cross-linking agent or functional monomer for creating polymers with specific light-responsive or energetic properties.
• Energetic Materials Precursor: Investigated in controlled research environments for the development of specialized chemical compounds.

Basic Information

Product Name	2-Nitro-5-Azidobenzoic Acid
CAS No.	60117-34-2
Molecular Formula	C7H4N4O4
Molecular Weight	208.13 g/mol
Synonyms	5-Azido-2-nitrobenzoic Acid; Benzoic acid, 5-azido-2-nitro-; 2-Nitro-5-azidobenzoic acid; 5-Azido-2-nitro-benzoic acid; 2-Nitro-5-azidobenzoic acid (ACI); 60117-34-2 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Nitro-5-Azidobenzoic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and the presence of an azido group, avoid exposure to direct light, heat sources, and strong mechanical shock. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.