Description

(2R)-1,2,12,12Aα-Tetrahydro-5,6Aα-Dihydroxy-8,9-Dimethoxy-2α-(1-Methylvinyl)[1]Benzopyrano[3,4-B]Furo[2,3-H][1]Benzopyran-6(6Ah)-One is a complex, high-purity organic compound belonging to the benzopyranofurobenzopyran class, valued for its intricate stereochemistry and functional groups. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a potential synthetic intermediate or a lead compound for novel therapeutics. It is primarily sought by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of complex molecules for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) with potential biological activity.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold in structure-activity relationship (SAR) studies to develop new drug candidates.
• Process Development: Employed in the optimization and scale-up of synthetic routes for complex heterocyclic compounds in pilot plants.
• Biochemical Research: Investigated for potential interactions with biological targets due to its fused polycyclic structure, which is common in many natural products with bioactivity.
• Fine Chemical Synthesis: Utilized in the custom synthesis of specialty chemicals requiring high stereochemical purity and complex molecular architecture.
• Academic Research: Provides a valuable compound for studies in advanced organic synthesis, asymmetric catalysis, and natural product chemistry.

Basic Information

Product Name	(2R)-1,2,12,12Aα-Tetrahydro-5,6Aα-Dihydroxy-8,9-Dimethoxy-2α-(1-Methylvinyl)[1]Benzopyrano[3,4-B]Furo[2,3-H][1]Benzopyran-6(6Ah)-One
CAS No.	60077-63-6
Molecular Formula	C24H22O8
Molecular Weight	438.43 g/mol
Synonyms	Rocaglaol; (-)-Rocaglaol; 1H-[1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-5,6a-dihydroxy-8,9-dimethoxy-2a-(1-methylethenyl)-, (2R,2aR,5S,6aS,12aS)-; AG-L-596; CCG-204791; NSC 319795; Roc-A; Flavagline derivative
EINECS	Contact for details

Quality Control

Our (2R)-1,2,12,12Aα-Tetrahydro-5,6Aα-Dihydroxy-8,9-Dimethoxy-2α-(1-Methylvinyl)[1]Benzopyrano[3,4-B]Furo[2,3-H][1]Benzopyran-6(6Ah)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (NMR, MS). Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.