Description

3,4-Dimethoxyphenylacetic Acid Hydrazide is a versatile aromatic hydrazide derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, combining a protected phenylacetic acid moiety with a reactive hydrazide group, enabling the construction of complex heterocycles and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality raw materials for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting neurological and cardiovascular systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Heterocyclic Chemistry: Essential building block for constructing pyrazoles, pyrazolines, and other nitrogen-containing heterocycles.
• Bioconjugation & Linker Chemistry: The hydrazide group is utilized for coupling with aldehydes and ketones in bioconjugation applications and linker synthesis.
• Research & Development: Serves as a standard reagent in academic and industrial R&D for method development and novel compound library synthesis.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method validation and impurity profiling.

Basic Information

Product Name	3,4-Dimethoxyphenylacetic Acid Hydrazide
CAS No.	60075-23-2
Molecular Formula	C10H14N2O3
Molecular Weight	210.23 g/mol
Synonyms	3,4-Dimethoxybenzeneacetic Acid Hydrazide; (3,4-Dimethoxyphenyl)acetic Acid Hydrazide; Veratric Acid Hydrazide; 3,4-Dimethoxyphenylacetohydrazide; 2-(3,4-Dimethoxyphenyl)acetohydrazide; NSC 403697; 60075-23-2
EINECS	Contact for details

Quality Control

Our 3,4-Dimethoxyphenylacetic Acid Hydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.