Description

1,6-Naphthyridin-2(1H)-One, 4-Hydroxy- is a high-purity heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. This specialized intermediate is valued for its unique fused-ring structure, which provides a versatile scaffold for constructing complex molecules with targeted biological or material properties. It is primarily sought after by research institutions and pharmaceutical developers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for research into kinase inhibitors and other therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in drug discovery programs targeting various disease pathways.
• Agrochemical Development: Serves as a building block for creating new candidates for crop protection agents and herbicides.
• Material Science: Investigated for its potential in creating organic electronic materials, ligands for metal-organic frameworks (MOFs), or advanced polymers.
• Chemical Synthesis: Employed in academic and industrial R&D for the preparation of complex naphthyridine derivatives and other fused heterocycles.

Basic Information

Product Name	1,6-Naphthyridin-2(1H)-One, 4-Hydroxy-
CAS No.	60058-17-5
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	4-Hydroxy-1,6-naphthyridin-2(1H)-one; 4-Hydroxy-1H-1,6-naphthyridin-2-one; 4-Hydroxy-2(1H)-1,6-naphthyridinone; 4-Hydroxy-1,6-naphthyridin-2-one; 1,6-Naphthyridin-2-ol, 4-hydroxy-; 2H-1,6-Naphthyridine-2-one, 4-hydroxy-; 4-Hydroxy-1,6-naphthyridin-2-ol; 1,2-Dihydro-4-hydroxy-1,6-naphthyridin-2-one
EINECS	Contact for details

Quality Control

Our 1,6-Naphthyridin-2(1H)-One, 4-Hydroxy- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.