Description

4-Hydroxy-1,5-naphthyridin-2(1H)-one is a heterocyclic organic compound belonging to the naphthyridine class, serving as a versatile and high-value pharmaceutical intermediate. Its core value lies in its role as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex nitrogen-containing heterocycles. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and advanced material science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting infectious diseases, oncology, and central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: Employed in organic synthesis to construct more complex polycyclic frameworks and functionalized naphthyridine derivatives.
• Material Science: Investigated for potential applications in creating organic electronic materials, ligands for catalysis, and fluorescent markers.
• Academic & R&D: Serves as a standard or starting material in university and corporate research laboratories for methodological studies and novel compound discovery.

Basic Information

Product Name	4-Hydroxy-1,5-Naphthyridin-2(1H)-One
CAS No.	60058-16-4
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	1,5-Naphthyridin-2(1H)-one, 4-hydroxy-; 4-Hydroxy-1,5-naphthyridin-2(1H)-one; 4-Hydroxy-1,5-naphthyridin-2-one; 2-Hydroxy-1,5-naphthyridin-4(1H)-one (tautomer); 1,5-Naphthyridin-4-ol-2-one; 4-Hydroxy-1,5-dihydro-2H-1,5-naphthyridin-2-one
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-1,5-naphthyridin-2(1H)-one is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, residual solvents, and heavy metals, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.