Description

4,5-Dichloroisophthalic Acid Dimethyl Ester is a high-purity diester derivative of isophthalic acid, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized aromatic core with precise chlorine substitution, enabling the controlled synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries who require a reliable building block for developing active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the dichloro-substituted aromatic ring contributes to biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for constructing rigid, planar cores in liquid crystal displays (LCDs) and organic light-emitting diode (OLED) materials.
• Polymer & Resin Modifier: Incorporated into specialty polyesters, polyamides, and epoxy resins to enhance thermal stability, flame retardancy, and chemical resistance.
• Organic Synthesis Reagent: Utilized in coupling reactions and as a scaffold for constructing complex heterocyclic compounds in research and development.
• Coordination Chemistry Ligand: Acts as a precursor for dicarboxylate ligands used in metal-organic frameworks (MOFs) and catalytic complexes.

Basic Information

Product Name	4,5-Dichloroisophthalic Acid Dimethyl Ester
CAS No.	60047-49-6
Molecular Formula	C10H8Cl2O4
Molecular Weight	263.08 g/mol
Synonyms	Dimethyl 4,5-Dichloroisophthalate; 4,5-Dichloro-1,3-benzenedicarboxylic Acid Dimethyl Ester; Isophthalic Acid, 4,5-Dichloro-, Dimethyl Ester; 1,3-Benzenedicarboxylic acid, 4,5-dichloro-, dimethyl ester; 4,5-Dichlorobenzene-1,3-dicarboxylic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our 4,5-Dichloroisophthalic Acid Dimethyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we support compliance with relevant regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.