Description

2-Hydrazino-3-Methylbutanoic Acid is a specialized hydrazine derivative of a branched-chain amino acid, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its unique bifunctional structure, featuring both a reactive hydrazino group and a carboxylic acid moiety, enabling its use in the construction of complex heterocycles and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific stereochemical requirements.
• Peptidomimetics & Bioactive Molecules: Employed as a constrained amino acid analog in the design of peptide mimics and other biologically active compounds.
• Heterocyclic Chemistry: Serves as a precursor for the construction of pyrazoles, pyrazolines, and other nitrogen-containing heterocycles important in medicinal chemistry.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block in stereoselective synthesis routes.
• Research & Development: A valuable tool for chemical research in academic and industrial R&D laboratories exploring new synthetic methodologies.

Basic Information

Product Name	2-Hydrazino-3-Methylbutanoic Acid
CAS No.	60047-26-9
Molecular Formula	C5H12N2O2
Molecular Weight	132.16 g/mol
Synonyms	L-2-Hydrazino-3-methylbutyric Acid; (2S)-2-Hydrazinyl-3-methylbutanoic Acid; 3-Methyl-2-hydrazinobutanoic Acid; 2-Hydrazino-3-methylbutyric Acid; Valine hydrazide acid
EINECS	Contact for details

Quality Control

Our 2-Hydrazino-3-Methylbutanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.