Description

4-Bromomethyl-1-Methyl-2,6,7-Trioxabicyclo[2.2.2]Octane is a specialized bicyclic orthoester derivative, valued for its role as a versatile building block in advanced organic synthesis. Its unique structure, featuring a reactive bromomethyl group, makes it a critical intermediate for introducing complex, protected functionalities into target molecules. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex molecular architectures.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its bicyclic structure can contribute to unique biological activity.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Material Science Research: Employed in creating advanced organic materials, such as liquid crystals or molecular cages, due to its rigid, three-dimensional scaffold.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying biological processes, leveraging its reactive handle for bioconjugation.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	4-Bromomethyl-1-Methyl-2,6,7-Trioxabicyclo[2.2.2]Octane
CAS No.	60028-14-0
Molecular Formula	C8H11BrO3
Molecular Weight	235.08 g/mol
Synonyms	1-Methyl-4-(bromomethyl)-2,6,7-trioxabicyclo[2.2.2]octane; 4-(Bromomethyl)-1-methyl-2,6,7-trioxabicyclo[2.2.2]octane; Bicyclo[2.2.2]octane, 4-(bromomethyl)-1-methyl-2,6,7-trioxa-; 1-Methyl-4-bromomethyl-2,6,7-trioxabicyclo[2.2.2]octane; Bromomethyl Methyl TRIOXA Bicyclooctane
EINECS	Contact for details

Quality Control

Our 4-Bromomethyl-1-Methyl-2,6,7-Trioxabicyclo[2.2.2]Octane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.