Description

4-Butyl-2,6,7-Trioxabicyclo[2.2.2]Octane is a specialized bicyclic orthoester compound, valued for its unique reactivity as a protective group and building block in advanced organic synthesis. Its rigid, cage-like structure offers steric and electronic properties that are crucial for the controlled formation of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key protecting group for sensitive functional groups (e.g., diols, carboxylic acids) during multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its orthoester functionality enables specific molecular modifications.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal stability and specific degradation profiles.
• Material Science: Employed in the synthesis of dendrimers, cages, and other precisely engineered nanostructures for electronic or catalytic applications.
• Organic Synthesis Reagent: Functions as a versatile reagent for transacetalization and other condensation reactions under mild conditions.
• Flavor & Fragrance Industry: Utilized in the synthesis of complex ester compounds that require controlled release or specific stereochemistry.

Basic Information

Product Name	4-Butyl-2,6,7-Trioxabicyclo[2.2.2]Octane
CAS No.	60028-09-3
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	1-Butyl-4,10-dioxa-3,5,7,9,11-pentaoxatricyclo[5.3.1.13,9]dodecane; 4-n-Butyl-2,6,7-trioxa-1-borabicyclo[2.2.2]octane (common naming variant); Butyl Bicyclic Orthoester; BBO (abbreviation); 4-Butyl-1-bora-2,6,7-trioxabicyclo[2.2.2]octane; Orthoester, bicyclic, butyl-; 60028-09-3
EINECS	Contact for details

Quality Control

Our 4-Butyl-2,6,7-Trioxabicyclo[2.2.2]Octane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent hydrolysis and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Specific Gravity (20°C)	1.05 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.