Description

4-Bromophthalic Acid is a versatile brominated aromatic dicarboxylic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive bromine substituent and two carboxylic acid functional groups, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery, ligand synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those with phthalimide or phthalic anhydride cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the bromine atom facilitates further coupling reactions.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-organic frameworks (MOFs) and homogeneous catalysis.
• Polymer Chemistry: A monomer for synthesizing high-performance polyimides, polyamides, and other engineering plastics with enhanced thermal and chemical resistance.
• Dyestuff and Pigment Manufacturing: Intermediate in the production of brominated anthraquinone and other complex organic colorants.
• Organic Electronic Materials: Used in research for developing novel organic semiconductors and light-emitting materials.
• Cross-coupling Reactions: The bromine atom makes it a suitable substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Academic and R&D: A valuable reagent for methodological studies and the synthesis of novel chemical entities in research laboratories.

Basic Information

Product Name	4-Bromophthalic Acid
CAS No.	6968-28-1
Molecular Formula	C8H5BrO4
Molecular Weight	245.03 g/mol
Synonyms	4-Bromobenzene-1,2-dicarboxylic Acid; 1,2-Benzenedicarboxylic Acid, 4-Bromo-; 4-Bromo-1,2-benzenedicarboxylic Acid; NSC 403107; 4-Bromophthalic Acid; p-Bromophthalic Acid; 4-Bromophthalsäure (German); Acide 4-bromophtalique (French)
EINECS	230-165-7

Quality Control

Our 4-Bromophthalic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and titration for acid value, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.