Description

N-(2,4-Difluorophenyl)Maleamic Acid is a high-purity organic intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the difluorophenyl moiety can improve activity and selectivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker for designing enzyme inhibitors, probes, and other bioactive tools due to its reactive maleamic acid group.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for constructing heterocyclic compounds and complex molecular architectures via cyclization and condensation reactions.

Basic Information

Product Name	N-(2,4-Difluorophenyl)Maleamic Acid
CAS No.	6954-64-9
Molecular Formula	C10H7F2NO3
Molecular Weight	227.16 g/mol
Synonyms	2,4-Difluorophenylmaleamic Acid; Maleamic Acid, N-(2,4-Difluorophenyl)-; (2Z)-4-Oxo-4-[(2,4-difluorophenyl)amino]but-2-enoic Acid; 2-Butenedioic Acid, 4-[(2,4-Difluorophenyl)amino]-4-oxo-, (2Z)-; 6954-64-9; N-(2,4-Difluorophenyl)maleamic acid
EINECS	Contact for details

Quality Control

Our N-(2,4-Difluorophenyl)Maleamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.