Description

6-Nitroquinazolin-4(3H)-One is a versatile and high-value nitro-substituted quinazolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its reactive nitro and carbonyl groups, which enable precise functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and pesticides by acting as a precursor for heterocyclic active ingredients.
• Material Science Precursor: Employed in the creation of organic semiconductors, fluorescent dyes, and photoactive materials due to its electron-deficient aromatic structure.
• Chemical Synthesis Reagent: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Academic & R&D: Utilized in universities and research institutions for methodological development in heterocyclic chemistry and nitro-group transformations.

Basic Information

Product Name	6-Nitroquinazolin-4(3H)-One
CAS No.	6943-17-5
Molecular Formula	C8H5N3O3
Molecular Weight	191.15 g/mol
Synonyms	6-Nitro-4(3H)-quinazolinone; 4-Hydroxy-6-nitroquinazoline; 6-Nitroquinazolin-4-ol; 6-Nitro-3,4-dihydro-4-oxoquinazoline; 6-Nitro-4-quinazolinol; 6943-17-5; Quinazolin-4(3H)-one, 6-nitro-
EINECS	Contact for details

Quality Control

Our 6-Nitroquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.