Description

Boc-Glycine Hydrazide CAS NO 6926-09-6 is a protected amino acid derivative where the glycine moiety is functionalized with a hydrazide group and the amine is protected by a tert-butoxycarbonyl (Boc) group. This molecular architecture makes it a versatile and crucial building block in organic synthesis, particularly for the preparation of peptide hydrazides and other bioactive compounds. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Peptide Synthesis: A key intermediate for the preparation of peptide hydrazides via the azide coupling method, a classical approach in peptide chain elongation.
• Medicinal Chemistry & Drug Discovery: Serves as a scaffold or precursor for synthesizing libraries of compounds with potential pharmacological activity.
• Bioconjugation: The reactive hydrazide group can be used for site-specific conjugation with aldehydes or ketones, useful in labeling proteins or creating antibody-drug conjugates (ADCs).
• Heterocyclic Chemistry: Employed in the synthesis of various nitrogen-containing heterocycles, such as pyrazoles and triazoles, which are common motifs in agrochemicals and pharmaceuticals.
• Protecting Group Chemistry: The Boc-protected amine allows for selective deprotection under mild acidic conditions, enabling orthogonal synthesis strategies in complex molecule assembly.
• Academic & Industrial Research: Used as a standard reagent in chemical research for method development and exploring new synthetic pathways.

Basic Information

Product Name	Boc-Glycine Hydrazide
CAS No.	6926-09-6
Molecular Formula	C7H15N3O3
Molecular Weight	189.21 g/mol
Synonyms	N-(tert-Butoxycarbonyl)glycine hydrazide; N-Boc-glycine hydrazide; Boc-Gly-NHNH2; Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, hydrazide; (tert-Butoxycarbonylamino)acetic acid hydrazide; 2-[(tert-Butoxycarbonyl)amino]acetohydrazide; BOC-Gly-OH-NHNH2; Boc-Glycine Hydrazine
EINECS	Contact for details

Quality Control

Our Boc-Glycine Hydrazide is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific purity requirements, we offer material tailored to research-grade or custom synthesis specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.