Description

2,3,5,9,10,10A-Hexahydro-10-Hydroxy-α-Methyl-1H,10Bh-Benzo[Ij]Quinolizine-10B-Propionic Acid Methyl Ester is a complex heterocyclic organic compound with a benzoquinolizine core structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its intricate fused ring system and functional groups make it a valuable building block for constructing sophisticated molecular architectures. This compound is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular systems.
• Organic Synthesis Building Block: Utilized in research laboratories for constructing complex heterocyclic frameworks and exploring new chemical spaces.
• Fine Chemical Production: Serves as a specialized intermediate in the manufacture of high-purity, low-volume specialty chemicals for agrochemicals or material science.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological development and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale, optimizing yield and purity for commercial production.

Basic Information

Product Name	2,3,5,9,10,10A-Hexahydro-10-Hydroxy-α-Methyl-1H,10Bh-Benzo[Ij]Quinolizine-10B-Propionic Acid Methyl Ester
CAS No.	6900-93-2
Molecular Formula	C18H25NO3
Molecular Weight	303.40 g/mol
Synonyms	Methyl 10-hydroxy-α-methyl-1,2,3,5,9,10a-hexahydro-10bH-benzo[ij]quinolizine-10b-propanoate; 10bH-Benzo[ij]quinolizine-10b-propanoic acid, 1,2,3,5,9,10a-hexahydro-10-hydroxy-α-methyl-, methyl ester; Methyl (10bS)-10-hydroxy-α-methyl-1,2,3,5,9,10a-hexahydro-10bH-benzo[ij]quinolizine-10b-propanoate (stereoisomer); Benzoquinolizine propionate methyl ester derivative; Advanced benzoquinolizine intermediate.
EINECS	Contact for details

Quality Control

Every batch of our 2,3,5,9,10,10A-Hexahydro-10-Hydroxy-α-Methyl-1H,10Bh-Benzo[Ij]Quinolizine-10B-Propionic Acid Methyl Ester is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.