Description

Spirost-5-En-7-One, 3-Hydroxy-, (5B,25R)- CAS NO 6877-72-1 is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry at the 5B and 25R positions makes it a critical building block for ensuring the precise biological activity of final pharmaceutical compounds. This compound is essential for research and development laboratories, as well as production facilities, in the pharmaceutical and fine chemical sectors focused on steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the multi-step synthesis of steroidal drugs, including certain hormones, anti-inflammatory agents, and cardiovascular medications.
• Fine Chemical Synthesis: Used as a starting material or advanced intermediate for constructing complex natural products and novel chemical entities in organic chemistry research.
• Biochemical Research: Serves as a reference standard or probe in metabolic pathway studies and enzymatic reactions involving sterol biosynthesis.
• Steroid Chemistry Development: Employed in academic and industrial R&D for developing new synthetic methodologies and exploring structure-activity relationships (SAR) of steroid analogs.

Basic Information

Product Name	Spirost-5-En-7-One, 3-Hydroxy-, (5B,25R)-
CAS No.	6877-72-1
Molecular Formula	C27H40O4
Molecular Weight	428.61 g/mol
Synonyms	(25R)-Spirost-5-en-3β-ol-7-one; 3β-Hydroxy-(25R)-spirost-5-en-7-one; 7-Ketodiosgenin; Diosgenone; (25R)-7-Oxodiosgenin; 7-Oxo-(25R)-spirost-5-en-3β-ol; 3β-Hydroxy-5α-spirost-7-one (related isomer); SMILES: CC12CCC(=O)C=C1CCC3C2(CCC4(C3CCC5(C4CC=C(C5)O)C)C)C
EINECS	Contact for details

Quality Control

Our Spirost-5-En-7-One, 3-Hydroxy-, (5B,25R)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.