Description

1-Benzocyclobutenecarbonitrile is a specialized, high-value organic building block featuring a strained four-membered ring fused to a benzonitrile moiety. This unique molecular architecture makes it a critical intermediate for synthesizing complex pharmaceuticals and advanced materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring strained ring systems or specific nitrile functionality for further transformation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the benzocyclobutene core imparts unique biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers with tailored thermal or mechanical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems, leveraging the reactivity of the cyclobutene ring.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including ring-opening reactions and [2+2] cycloadditions.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals requiring a precise aromatic nitrile structure.

Basic Information

Product Name	1-Benzocyclobutenecarbonitrile
CAS No.	6809-91-2
Molecular Formula	C10H7N
Molecular Weight	141.17 g/mol
Synonyms	1-Cyanobenzocyclobutene; Benzocyclobutene-1-carbonitrile; 1-Cyano-1,2-dihydrobenzocyclobutene; 1,2-Dihydro-1-cyanobenzocyclobutene; BCBN; o-Xylylene cyanide; Bicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-Benzocyclobutenecarbonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.