Description

n-[(20S)-20-(Dimethylamino)-5α-Pregnan-3α-Yl]-N,3-Dimethyl-2-Butenamide CAS NO 6792-14-9 is a high-purity, synthetic steroid derivative with a complex molecular structure, primarily utilized as a critical pharmaceutical intermediate. This compound is valued for its role in the research and development of novel therapeutic agents, particularly in the field of neuroactive steroids and hormone modulators. It is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on advanced medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced steroid-based active pharmaceutical ingredients (APIs).
• Neurosteroid Research: Used in preclinical studies to investigate modulators of GABA-A receptors and other central nervous system targets.
• Hormone Analog Development: Serves as a precursor for creating novel analogs with potential therapeutic applications in endocrinology.
• Medicinal Chemistry R&D: A valuable reference standard and starting material for structure-activity relationship (SAR) studies in drug discovery.
• Biochemical Research: Employed in studies exploring steroid-protein interactions and metabolic pathways.
• GMP Manufacturing: Supplied under controlled conditions for use in cGMP-compliant production processes for clinical trial materials.

Basic Information

Product Name	n-[(20S)-20-(Dimethylamino)-5α-Pregnan-3α-Yl]-N,3-Dimethyl-2-Butenamide
CAS No.	6792-14-9
Molecular Formula	C₂₉H₄₈N₂O
Molecular Weight	440.71 g/mol
Synonyms	Pregnenolone dimethylamino butenamide derivative; (20S)-20-(Dimethylamino)-5α-pregnan-3α-yl N,3-dimethyl-2-butenamide; 3α-[(Dimethylamino)methyl]-5α-pregnan-20-one N,N-dimethylcrotonamide; Alfaxalone related intermediate; 6792-14-9; 5α-Pregnan-3α-ol, 20-(dimethylamino)-, 3-(2-methyl-1-oxo-2-buten-1-yl) ester, (20S)-
EINECS	Contact for details

Quality Control

Our n-[(20S)-20-(Dimethylamino)-5α-Pregnan-3α-Yl]-N,3-Dimethyl-2-Butenamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) that detail all specifications, ensuring compliance with the rigorous standards required for pharmaceutical R&D and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.