Description

(3S)-7-Bromo-1,2,3,8B-Tetrahydro-3,6,8Bβ-Trimethyl-3Ah-Cyclopenta[B]Benzofuran-3Aβ-Methanol CAS NO 6790-64-3 is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined cyclopenta[b]benzofuran structure. This compound is of significant value for its role as a key chiral building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold or precursor for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new lead structures.
• Process Chemistry Development: Employed in route scouting and optimization studies for the scalable production of complex active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized in studies exploring novel catalytic or enzymatic methodologies due to its defined stereogenic centers.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(3S)-7-Bromo-1,2,3,8B-Tetrahydro-3,6,8Bβ-Trimethyl-3Ah-Cyclopenta[B]Benzofuran-3Aβ-Methanol
CAS No.	6790-64-3
Molecular Formula	C₁₇H₂₁BrO₂
Molecular Weight	337.25 g/mol
Synonyms	7-Bromo-1,2,3,8b-tetrahydro-3,6,8bβ-trimethyl-3ah-cyclopenta[b]benzofuran-3aβ-methanol; (3S)-7-Bromo-1,2,3,8b-tetrahydro-3,6,8bβ-trimethyl-3ah-cyclopenta[b]benzofuran-3aβ-methanol; 7-Bromo-3aβ-(hydroxymethyl)-3,6,8bβ-trimethyl-1,2,3,3a,8,8b-hexahydrocyclopenta[b]benzofuran; 7-Bromo-3aβ-(hydroxymethyl)-3,6,8bβ-trimethyl-1,2,3,3a,8,8b-hexahydro-3ah-cyclopenta[b]benzofuran; Brominated Cyclopenta[B]Benzofuran Methanol Derivative; CAS 6790-64-3
EINECS	Contact for details

Quality Control

Our (3S)-7-Bromo-1,2,3,8B-Tetrahydro-3,6,8Bβ-Trimethyl-3Ah-Cyclopenta[B]Benzofuran-3Aβ-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.