Description

1H-Pyrazole-1-Acetic Acid, 4-Iodo- is a high-value iodinated pyrazole derivative, a versatile chemical building block prized for its unique halogenated heterocyclic structure. This compound is critical for advanced organic synthesis, enabling the introduction of both a reactive iodo group and a functional acetic acid moiety into target molecules. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: The iodine atom facilitates cross-coupling reactions (e.g., Suzuki, Sonogashira), while the acetic acid group allows for further derivatization via esterification or amide coupling.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Investigated for the synthesis of advanced organic materials and functional polymers.

Basic Information

Product Name	1H-Pyrazole-1-Acetic Acid, 4-Iodo-
CAS No.	6752-13-2
Molecular Formula	C5H5IN2O2
Molecular Weight	252.01 g/mol
Synonyms	4-Iodo-1H-pyrazole-1-acetic acid; 4-Iodopyrazole-1-acetic acid; 1-(Carboxymethyl)-4-iodo-1H-pyrazole; 4-Iodo-1H-pyrazol-1-ylacetic acid; 4-Iodo-pyrazole-1-yl-acetic acid; 1H-Pyrazole-1-acetic acid, 4-iodo-; (4-Iodo-1H-pyrazol-1-yl)acetic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-1-Acetic Acid, 4-Iodo- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.