Description

2-o-Methyl-B-D-n-Acetylneuraminicacidmethylester CAS NO 6730-43-4 is a chemically modified derivative of N-acetylneuraminic acid, a key sialic acid. This compound is a crucial advanced intermediate in the synthesis of more complex sialylated glycoconjugates and inhibitors. It is primarily required by research institutions and pharmaceutical developers working in glycobiology, antiviral drug discovery, and diagnostic reagent formulation.

Application

• Glycobiology Research: Used as a key building block for synthesizing sialic acid analogs to study cell surface recognition, signaling, and adhesion processes.
• Antiviral Drug Development: Serves as a precursor for designing neuraminidase inhibitors targeting influenza and other viruses that utilize sialic acid receptors.
• Diagnostic Reagents: Employed in the development of enzyme substrates and probes for detecting sialidase (neuraminidase) activity in clinical and research assays.
• Carbohydrate Chemistry: Acts as a protected intermediate for the chemical and enzymatic synthesis of complex oligosaccharides and glycopeptides.
• Bioconjugation: Utilized to introduce sialic acid motifs onto proteins, lipids, or surfaces for creating bioactive materials and studying carbohydrate-protein interactions.

Basic Information

Product Name	2-o-Methyl-B-D-n-Acetylneuraminicacidmethylester
CAS No.	6730-43-4
Molecular Formula	C13H23NO9
Molecular Weight	337.32 g/mol
Synonyms	Methyl 2-O-methyl-β-D-N-acetylneuraminate; 2-O-Methyl-N-acetylneuraminic acid methyl ester; 2-OMe-Neu5Ac methyl ester; Methyl (5-acetamido-3,5-dideoxy-2-O-methyl-D-glycero-α-D-galacto-non-2-ulopyranosid)onate; 2-O-Methyl-5-N-acetyl-β-D-neuraminic acid methyl ester; 2-O-Methyl-Neu5Ac-OMe; 2-O-Methyl sialic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-o-Methyl-B-D-n-Acetylneuraminicacidmethylester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.