Description

o-(Tetrahydro-2H-Pyran-2-Yl)Hydroxylamine is a versatile protected hydroxylamine derivative, a crucial building block in advanced organic synthesis. Its primary value lies in its ability to introduce the hydroxylamine functional group in a protected form, enabling complex transformations while preventing unwanted side reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of oximes, hydroxamic acids, and nitrones used in drug discovery and development.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring hydroxylamine functionality.
• Peptide Modification: Acts as a reagent for the selective modification of amino acid side chains or peptide termini.
• Polymer Chemistry: Serves as a functional monomer or chain transfer agent in the synthesis of specialty polymers with tailored properties.
• Ligand Synthesis: Building block for creating complex chelating agents and ligands used in catalysis and metal coordination chemistry.
• Cross-Coupling Reactions: Employed in palladium-catalyzed and other cross-coupling methodologies to construct C-N bonds.

Basic Information

Product Name	o-(Tetrahydro-2H-Pyran-2-Yl)Hydroxylamine
CAS No.	6723-30-4
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	THP-Protected Hydroxylamine; O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine; 2-(Aminooxy)tetrahydro-2H-pyran; N-(Tetrahydro-2-pyranyl)hydroxylamine; 2-(Hydroxyamino)tetrahydropyran; THP-ONH2; O-THP-hydroxylamine; 2-(Aminooxy)oxane
EINECS	Contact for details

Quality Control

Our o-(Tetrahydro-2H-Pyran-2-Yl)Hydroxylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.