Description

4-Iodo-Pyrazole-3-Carboxylic Acid is a halogenated pyrazole derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and an iodine substituent, makes it a critical intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of potential drug candidates, especially in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the pyrazole core's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Building block for synthesizing organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for client R&D projects.

Basic Information

Product Name	4-Iodo-Pyrazole-3-Carboxylic Acid
CAS No.	6647-93-4
Molecular Formula	C4H3IN2O2
Molecular Weight	237.98 g/mol
Synonyms	4-Iodo-1H-pyrazole-3-carboxylic acid; 4-Iodo-3-pyrazolecarboxylic acid; 3-Carboxy-4-iodopyrazole; 4-Iodo-1H-pyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 4-iodo-; 4-Iodo-pyrazole-3-carboxylic acid; 4-Iodo-3-carboxypyrazole
EINECS	Contact for details

Quality Control

Our 4-Iodo-Pyrazole-3-Carboxylic Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While typically supplied as a standard R&D grade, production can be aligned with cGMP guidelines for advanced project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.