Description

2-Bromo-4-Methylphenol (CAS NO 6627-55-0) is a halogenated phenolic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a methyl group on the phenol ring, makes it an essential intermediate for constructing complex molecules. This high-purity intermediate is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring brominated aromatic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides where the bromophenol moiety imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Monomer: Employed in the development of specialty polymers, resins, and functional materials with enhanced flame retardancy or specific electronic properties.
• Dye and Pigment Intermediate: Acts as a starting material for the manufacture of certain brominated dyes and organic pigments.
• Research & Development: A valuable reagent in academic and industrial research labs for exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	2-Bromo-4-Methylphenol
CAS No.	6627-55-0
Molecular Formula	C7H7BrO
Molecular Weight	187.04 g/mol
Synonyms	4-Methyl-2-bromophenol; 2-Bromo-p-cresol; o-Bromo-p-cresol; 2-Bromo-4-hydroxytoluene; 1-Bromo-2-hydroxy-5-methylbenzene; Phenol, 2-bromo-4-methyl-; NSC 403697
EINECS	229-575-6

Quality Control

Our 2-Bromo-4-Methylphenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.