Description

2,2,2-Trimethylacetanilide is a specialized organic compound belonging to the class of anilides, characterized by its unique sterically hindered structure. This molecular architecture makes it a valuable intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and fine chemicals. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules where specific steric and electronic properties are required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring bulky, electron-donating anilide groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other performance chemicals where its structure imparts specific properties.
• Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical entities.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal-catalyzed reactions.

Basic Information

Product Name	2,2,2-Trimethylacetanilide
CAS No.	6625-74-7
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	N-(2,2,2-Trimethylacetyl)aniline; 2,2,2-Trimethyl-N-phenylacetamide; α,α,α-Trimethylacetanilide; Trimethylacetanilide; Pivalanilide; N-Phenylpivalamide; N-Phenyl-2,2-dimethylpropanamide
EINECS	229-579-5

Quality Control

Our 2,2,2-Trimethylacetanilide is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data to support your quality assurance protocols. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.