Description

1-(Chloromethyl)-5-Nitro-Naphthalene is a specialized naphthalene derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a reactive chloromethyl group and a nitro substituent, makes it a critical building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those with naphthalene-based scaffolds, for therapeutic areas such as oncology and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its structure can be incorporated into active molecules.
• Organic Light-Emitting Diodes (OLEDs) Research: Serves as a starting material for synthesizing electron-transport or emissive layer components in organic electronic materials.
• Dye and Pigment Chemistry: Acts as an intermediate for creating specialized nitro- and amino-naphthalene based dyes and colorants.
• Cross-coupling Reactions: The chloromethyl group facilitates further functionalization via palladium-catalyzed or other metal-mediated coupling reactions.
• Polymer Modification: Can be used to introduce functional naphthalene units into polymer chains to alter physical or optical properties.

Basic Information

Product Name	1-(Chloromethyl)-5-Nitro-Naphthalene
CAS No.	6625-54-3
Molecular Formula	C₁₁H₈ClNO₂
Molecular Weight	221.64 g/mol
Synonyms	5-Nitro-1-(chloromethyl)naphthalene; 1-Chloromethyl-5-nitronaphthalene; (5-Nitro-1-naphthyl)methyl chloride; 5-Nitro-1-naphthalenemethyl chloride; NSC 406079; 1-Naphthalenemethyl chloride, 5-nitro-; α-Chloro-5-nitronaphthalenemethane
EINECS	229-588-4

Quality Control

Our 1-(Chloromethyl)-5-Nitro-Naphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.