Description

2-Bromo-3-Chloro-3-Phenyl-Propanoic Acid is a versatile halogenated phenylpropanoic acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring bromine and chlorine substituents on the β-carbon, makes it a valuable precursor for constructing complex molecules with high stereochemical control. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated structure for bioactive molecule design.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialized monomers or additives for advanced polymeric materials.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including investigations into halogenation reactions and stereoselective transformations.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Bromo-3-Chloro-3-Phenyl-Propanoic Acid
CAS No.	6622-79-3
Molecular Formula	C9H8BrClO2
Molecular Weight	263.52 g/mol
Synonyms	2-Bromo-3-chloro-3-phenylpropionic Acid; (±)-2-Bromo-3-chloro-3-phenylpropanoic Acid; 3-Phenyl-2-bromo-3-chloropropanoic Acid; β-Bromo-β-chlorohydrocinnamic Acid; NSC 163044; 2-Bromo-3-chloro-3-phenylpropanoic acid; DL-2-Bromo-3-chloro-3-phenylpropanoic Acid; Propanoic acid, 2-bromo-3-chloro-3-phenyl-
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chloro-3-Phenyl-Propanoic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.