Description

1,2,3,4-Tetra-o-Acetyl-6-o-Tosyl-β-D-Glucopyranose is a key protected monosaccharide derivative, widely used as a crucial synthetic intermediate in organic and medicinal chemistry. Its value lies in providing a versatile scaffold for the controlled synthesis of complex carbohydrates, glycoconjugates, and nucleoside analogs. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced glycosylation reagents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Glycosylation Reagent: Used in the stereoselective construction of glycosidic bonds for oligosaccharide and glycoconjugate synthesis.
• Carbohydrate Chemistry Research: Serves as a protected glucose derivative for studying enzymatic transformations and developing new synthetic methodologies.
• Glycobiology Probe Development: Utilized in the preparation of labeled sugar derivatives for metabolic pathway studies and diagnostic applications.
• Fine Chemical Synthesis: An intermediate in the production of specialty surfactants, chiral ligands, and complex natural product analogs.

Basic Information

Product Name	1,2,3,4-Tetra-o-Acetyl-6-o-Tosyl-β-D-Glucopyranose
CAS No.	6619-10-9
Molecular Formula	C23H28O11S
Molecular Weight	512.53 g/mol
Synonyms	6-O-Tosyl-1,2,3,4-tetra-O-acetyl-β-D-glucopyranose; β-D-Glucopyranose, 1,2,3,4-tetraacetate 6-(4-methylbenzenesulfonate); 1,2,3,4-Tetra-O-acetyl-6-O-tosyl-β-D-glucopyranose; 6-O-p-Tolylsulfonyl-1,2,3,4-tetra-O-acetyl-β-D-glucopyranose; Glucopyranose, 1,2,3,4-tetraacetate 6-(p-toluenesulfonate), β-D-; 6-O-Tosyl-β-D-glucopyranose tetraacetate; Tetraacetyl-6-tosylglucopyranose
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetra-o-Acetyl-6-o-Tosyl-β-D-Glucopyranose is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. All products undergo rigorous analytical testing, including HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-20° to -25° (c=1 in CHCl3)
Melting Point	142°C - 147°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.