Description

8-Chloroquinoline-6-Carboxylic Acid is a versatile and high-value heterocyclic building block, primarily used as a key intermediate in the synthesis of complex organic molecules. Its unique quinoline core functionalized with both a chlorine atom and a carboxylic acid group makes it an essential precursor for pharmaceutical research and development. This compound is particularly critical for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel anti-malarial, anti-cancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its bioactive quinoline scaffold.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and in the synthesis of complex molecules for material science applications.
• Chemical Research & Development: Acts as a standard or starting material in academic and industrial R&D for exploring new organic reactions and heterocyclic chemistry.
• Dye and Pigment Industry: Utilized as a precursor for the synthesis of specialized quinoline-based dyes and functional pigments.

Basic Information

Product Name	8-Chloroquinoline-6-Carboxylic Acid
CAS No.	6495-81-4
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	6-Carboxy-8-chloroquinoline; 8-Chloro-6-quinolinecarboxylic Acid; 8-Chloroquinoline-6-carboxylic acid; 8-Chloro-6-quinoline carboxylic acid; Quinoline-6-carboxylic acid, 8-chloro-; 8-Chloroquinaldinic Acid (less common); 8-Cl-6-QCA (abbreviation)
EINECS	Contact for details

Quality Control

Our 8-Chloroquinoline-6-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Standard Grade)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.