Description

6-Chloroquinoline-8-Carboxylic Acid is a versatile halogenated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring both a carboxylic acid and a chlorine substituent on the quinoline core, makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and anti-inflammatory compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline scaffold.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and production of organic semiconductors, dyes, and photoactive materials.
• Chemical Synthesis: A versatile building block for further functionalization, enabling the creation of libraries of compounds for high-throughput screening.

Basic Information

Product Name	6-Chloroquinoline-8-Carboxylic Acid
CAS No.	6456-78-6
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	8-Quinolinecarboxylic acid, 6-chloro-; 6-Chloro-8-quinolinecarboxylic acid; 6-Chloroquinoline-8-carboxylate; 6-Chloro-8-quinolinecarboxylate; 6-Chloro-8-carboxyquinoline; 6-Chloro-8-quinoline carboxylic acid; 6-Chloro-8-quinolylcarboxylic acid; 6-Chloro-8-quinolinecarboxylic acid (CAS 6456-78-6)
EINECS	229-268-1

Quality Control

Our 6-Chloroquinoline-8-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.