Description

Z-Glu-Nh2 CAS NO 6398-06-7 is a high-purity, protected glutamic acid derivative, specifically Nα-Carbobenzyloxy-L-glutamine. This compound is a crucial building block in peptide synthesis, offering a protected amine and side chain for controlled chemical reactions. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality intermediates for the development of novel therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of glutamine residues into peptide chains.
• Pharmaceutical Research: Used in the R&D of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules or surfaces.
• Combinatorial Chemistry: Employed in libraries for drug discovery to create diverse peptide structures.
• Biochemical Studies: Utilized as a standard or reagent in enzymatic and metabolic pathway research.
• Cosmetic Peptides: A potential raw material for synthesizing bioactive peptides used in advanced skincare formulations.

Basic Information

Product Name	Z-Glu-Nh2
CAS No.	6398-06-7
Molecular Formula	C₁₃H₁₆N₂O₅
Molecular Weight	280.28 g/mol
Synonyms	Nα-Carbobenzyloxy-L-glutamine; CBZ-L-Glutamine; Z-L-Glutamine; N-CBZ-L-glutamine; (S)-2-(((Benzyloxy)carbonyl)amino)-5-aminopentanedioic acid diamide; N-Carbobenzyloxy-L-glutamine; Nα-Z-L-Glutamine; L-Glutamine, N-[(phenylmethoxy)carbonyl]-
EINECS	229-001-9

Quality Control

Our Z-Glu-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	-14.0° to -16.0° (c=1 in AcOH)
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.