Description

(1R,4R,7R)-7-Nitrobicyclo[2.2.2]Oct-2-Ene CAS NO 6343-66-4 is a high-purity, chiral nitro-substituted bicyclic olefin, serving as a sophisticated building block in advanced organic synthesis. Its rigid bicyclo[2.2.2]octene scaffold and strategically positioned nitro group make it a valuable precursor for constructing complex, three-dimensional molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for applications in asymmetric synthesis, medicinal chemistry, and the development of novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and complex natural product analogs.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in the development and testing of new chiral catalysts.
• Agrochemical Development: Serves as a building block for creating novel, stereochemically defined pesticides and herbicides.
• Material Science: A precursor for functionalized polymers or advanced organic frameworks with specific optical or electronic properties.
• Academic & R&D Laboratories: Employed in methodological studies for new cycloaddition reactions, nitro-olefin chemistry, and stereoselective transformations.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring precise stereocontrol.

Basic Information

Product Name	(1R,4R,7R)-7-Nitrobicyclo[2.2.2]Oct-2-Ene
CAS No.	6343-66-4
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	(1R,4R,7R)-7-Nitro-2,5-norbornadiene; (1R,4R,7R)-7-Nitro-2,3,5,6-tetrahydro-1,4:5,8-dimethanonaphthalene; 7-Nitrobicyclo[2.2.2]octa-2,5-diene (stereospecific); (1R,4R,7R)-7-Nitro-2,5-dihydro-1,4-methanonaphthalene; endo-7-Nitrobicyclo[2.2.2]octa-2,5-diene; (1R,4R,7R)-7-Nitro-2,3,5,6-tetrahydro-1,4-methanonaphthalene; Nitro-substituted Bicyclo[2.2.2]octene
EINECS	Contact for details

Quality Control

Our (1R,4R,7R)-7-Nitrobicyclo[2.2.2]Oct-2-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.