Description

7-Chloro-8-Methyl-2-Phenylquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its bifunctional nature, featuring both a quinoline scaffold and an acid chloride group, making it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing advanced crop protection agents, such as herbicides and fungicides with quinoline cores.
• Material Science Research: Used in the creation of organic ligands for catalysis or functional organic materials like OLEDs and sensors.
• Chemical Biology Probes: Serves as a starting point for synthesizing fluorescent tags or activity-based probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API development.

Basic Information

Product Name	7-Chloro-8-Methyl-2-Phenylquinoline-4-Carbonyl Chloride
CAS No.	6338-22-3
Molecular Formula	C18H11Cl2NO
Molecular Weight	328.19 g/mol
Synonyms	4-Chlorocarbonyl-7-chloro-8-methyl-2-phenylquinoline; 2-Phenyl-7-chloro-8-methylquinoline-4-carbonyl chloride; 7-Chloro-8-methyl-2-phenyl-4-quinolinecarbonyl chloride; 7-Chloro-8-methyl-2-phenylquinoline-4-carboxylic acid chloride; Quinoline-4-carbonyl chloride, 7-chloro-8-methyl-2-phenyl-
EINECS	Contact for details

Quality Control

Our 7-Chloro-8-Methyl-2-Phenylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.