Description

H-D-Ala-Oet Hcl is a protected amino acid derivative, specifically the ethyl ester hydrochloride salt of D-alanine. This high-purity chiral building block is essential for the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced drug discovery, development of bioactive peptides, and fine chemical synthesis.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs) and therapeutic peptides.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected D-alanine residue to introduce specific structural features.
• Biochemical Research: Serves as a substrate or precursor in enzymatic studies and metabolic pathway investigations.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in the synthesis of enantiomerically pure compounds.
• Proteomics & Diagnostics: Can be used in the preparation of specialized reagents and labeled compounds for analytical applications.

Basic Information

Product Name	H-D-Ala-Oet Hcl
CAS No.	6331-09-5
Molecular Formula	C5H12ClNO2
Molecular Weight	153.61 g/mol
Synonyms	D-Alanine ethyl ester hydrochloride; (R)-2-Aminopropionic acid ethyl ester hydrochloride; Ethyl D-alaninate hydrochloride; H-D-Ala-OEt·HCl; D-Ala-OEt HCl; D-Alanine ethylester hydrochloride; (R)-Ethyl 2-aminopropanoate hydrochloride
EINECS	228-694-4

Quality Control

Our H-D-Ala-Oet Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.