Description

1-(3,4-Methylenedioxyphenyl)Ethanol is a versatile aromatic alcohol derivative of piperonal, serving as a key chiral intermediate in advanced organic synthesis. Its structural motif is highly valued for constructing complex molecules with specific stereochemistry, making it critical for ensuring product efficacy and purity. This compound is primarily sought by the pharmaceutical, agrochemical, and fine chemical industries for the research and development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its benzodioxole moiety contributes to biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals derived from piperonal.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in developing and testing new chiral catalysts and synthetic methodologies.
• Material Science: Investigated as a monomer or modifying agent for synthesizing specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	1-(3,4-Methylenedioxyphenyl)Ethanol
CAS No.	6329-73-3
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	1-(1,3-Benzodioxol-5-yl)ethanol; 1-(Benzo[d][1,3]dioxol-5-yl)ethan-1-ol; 5-(1-Hydroxyethyl)-1,3-benzodioxole; 3,4-(Methylenedioxy)benzyl carbinol; Piperonyl ethanol; α-Methylpiperonyl alcohol; (3,4-Methylenedioxyphenyl)methyl carbinol
EINECS	228-698-5

Quality Control

Every batch of 1-(3,4-Methylenedioxyphenyl)Ethanol is manufactured under a strict quality management system. We provide comprehensive analytical testing to ensure identity, purity, and consistency, with specifications tailored to meet the rigorous demands of pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), chiral purity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (Enantiomeric excess)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.