Description

5-Bromovanillic Acid is a versatile brominated derivative of vanillic acid, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized phenolic scaffold with both a carboxylic acid and a bromine substituent, enabling precise chemical modifications for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides and plant growth regulators, leveraging its halogenated phenolic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Incorporated into polymer backbones or as a functional monomer to impart specific thermal or chemical properties to advanced materials.
• Biochemical Research: Employed as a probe or substrate in enzymatic studies related to phenolic acid metabolism.
• Fine Chemical Production: Acts as a starting material for the synthesis of more complex vanillin derivatives and flavor/fragrance compounds.

Basic Information

Product Name	5-Bromovanillic Acid
CAS No.	6324-52-3
Molecular Formula	C8H7BrO4
Molecular Weight	247.04 g/mol
Synonyms	3-Methoxy-5-bromo-4-hydroxybenzoic Acid; 4-Hydroxy-3-methoxy-5-bromobenzoic Acid; 5-Bromo-4-hydroxy-3-methoxybenzoic Acid; 5-Bromovanillate; Vanillic Acid, 5-Bromo-; Benzoic acid, 4-hydroxy-3-methoxy-5-bromo-
EINECS	228-690-7

Quality Control

Our 5-Bromovanillic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Melting Point	245 - 250 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.