Description

4-Chloro-2-Butanone is a versatile chlorinated ketone intermediate with significant utility in organic synthesis. Its reactive carbonyl and chloromethyl groups make it a valuable building block for constructing more complex molecules in pharmaceutical and agrochemical research. This compound is essential for manufacturers and R&D laboratories involved in the synthesis of active pharmaceutical ingredients (APIs), specialty chemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key starting material or synthon in the multi-step synthesis of various drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and plant growth regulators, leveraging its reactive halogen functionality.
• Organic Chemical Research: Serves as a fundamental reagent in academic and industrial laboratories for exploring new organic reactions and methodologies.
• Specialty Chemical Manufacturing: Employed in the synthesis of dyes, pigments, flavors, fragrances, and other performance chemicals.
• Polymer Chemistry: Can act as a monomer or cross-linking agent in the development of specialty polymers and resins.

Basic Information

Product Name	4-Chloro-2-Butanone
CAS No.	6322-49-2
Molecular Formula	C4H7ClO
Molecular Weight	106.55 g/mol
Synonyms	1-Chloro-3-butanone; 4-Chlorobutan-2-one; 3-Oxobutyl chloride; Chloromethyl ethyl ketone; 4-Chloro-2-oxobutane; Butanone, 4-chloro-; NSC 60548
EINECS	228-672-8

Quality Control

Our 4-Chloro-2-Butanone is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total
Density (20°C)	1.08 - 1.12 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.