Description

D-(-)-Gulonic Acid γ-Lactone is a chiral lactone derivative of gulonic acid, serving as a key intermediate in the synthesis of ascorbic acid (Vitamin C) and other biologically active compounds. Its high chemical purity and defined stereochemistry are critical for ensuring the efficacy and safety of downstream pharmaceutical and nutraceutical products. This compound is essential for manufacturers in the pharmaceutical, food additive, and fine chemical synthesis industries seeking reliable, high-quality chiral building blocks.

Application

• Pharmaceutical Intermediate: A crucial precursor in the commercial and research-scale synthesis of L-ascorbic acid (Vitamin C) and its derivatives.
• Nutraceutical Production: Used in the manufacture of vitamin supplements and fortified food products.
• Fine Chemical Synthesis: Serves as a versatile chiral synthon for constructing complex molecules in organic and medicinal chemistry.
• Biochemical Research: Employed in metabolic pathway studies and as a standard in analytical laboratories.
• Cosmetic Ingredients: Potential intermediate for the production of skin-care active ingredients with antioxidant properties.

Basic Information

Product Name	D-(-)-Gulonic Acid γ-Lactone
CAS No.	6322-07-2
Molecular Formula	C6H10O6
Molecular Weight	178.14 g/mol
Synonyms	D-Gulono-1,4-lactone; D-(-)-Gulonolactone; L-Gulonic acid γ-lactone (enantiomer); (3R,4S,5S)-3,4,5-Trihydroxy-6-oxotetrahydro-2H-pyran-2-carboxylic acid; Gulonic acid lactone; Vitamin C intermediate
EINECS	228-668-6

Quality Control

Our D-(-)-Gulonic Acid γ-Lactone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profile analysis, to ensure it meets the high standards required for pharmaceutical and food-grade applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-20° to -24° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.