Description

(1S,2S)-2-(6-Dimethylaminopurin-9-Yl)Cyclohexan-1-Ol is a high-purity, stereochemically defined nucleoside analogue of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for the synthesis of novel antiviral and anticancer agents, where its specific stereochemistry is essential for biological activity. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the production of nucleotide-based therapeutics and diagnostic probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies targeting nucleoside-metabolizing enzymes.
• Pro-drug Development: Serves as a precursor molecule for the design of targeted pro-drugs with enhanced cellular uptake.
• Nucleotide Chemistry: Employed in the synthesis of modified oligonucleotides for antisense and RNAi therapeutic platforms.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies in drug discovery programs.

Basic Information

Product Name	(1S,2S)-2-(6-Dimethylaminopurin-9-Yl)Cyclohexan-1-Ol
CAS No.	6318-03-2
Molecular Formula	C₁₃H₁₉N₅O
Molecular Weight	261.32 g/mol
Synonyms	(1S,2S)-2-(6-Dimethylaminopurin-9-yl)cyclohexanol; (1S,2S)-2-(N⁶-Dimethyladenin-9-yl)cyclohexan-1-ol; 9-[(1S,2S)-2-Hydroxycyclohexyl]-N⁶,N⁶-dimethyladenine; 2-(6-Dimethylaminopurin-9-yl)cyclohexan-1-ol (1S,2S)-; N⁶,N⁶-Dimethyl-9-[(1S,2S)-2-hydroxycyclohexyl]adenine; (1S,2S)-2-(6-Dimethylamino-9H-purin-9-yl)cyclohexan-1-ol; DMAC-OH (cis-); cis-2-(6-Dimethylaminopurin-9-yl)cyclohexanol
EINECS	Contact for details

Quality Control

Our (1S,2S)-2-(6-Dimethylaminopurin-9-Yl)Cyclohexan-1-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates, and specifications can be aligned with client-specific pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (1S,2S) isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.