Description

5-Amino-2-Hydroxybenzoic Acid Hydrochloride is a high-purity organic salt derivative of 5-aminosalicylic acid, valued for its enhanced stability and solubility profile. This compound serves as a critical pharmaceutical intermediate and versatile building block in fine chemical synthesis. It is primarily required by manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of anti-inflammatory drugs, particularly mesalamine (5-aminosalicylic acid) analogs and related prodrugs.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Serves as a starting material for azo dyes and other complex colorants.
• Research & Development: Essential reagent in organic chemistry research for constructing heterocyclic compounds and complex molecular architectures.
• Chemical Synthesis: Employed in peptide coupling reactions and as a protecting group or directing agent in multi-step syntheses.

Basic Information

Product Name	5-Amino-2-Hydroxybenzoic Acid Hydrochloride
CAS No.	6291-36-7
Molecular Formula	C7H8NO3·HCl
Molecular Weight	189.60 g/mol (Free base: 153.14 g/mol)
Synonyms	5-Aminosalicylic Acid Hydrochloride; 5-ASA Hydrochloride; Mesalamine Hydrochloride; 2-Hydroxy-5-aminobenzoic Acid Hydrochloride; 5-Amino-2-hydroxybenzoic Acid Monohydrochloride; 4-Amino-2-carboxyphenol Hydrochloride; 5-Amino-2-hydroxybenzoic Acid HCl
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Hydroxybenzoic Acid Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) documenting purity, related substances, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.