Description

Cyclobutylamine Hydrochloride is a versatile organic salt widely utilized as a key building block in advanced chemical synthesis. Its value lies in providing a functionalized cyclobutane scaffold, a structure of significant interest in modern medicinal chemistry for creating novel molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the cyclobutane ring's unique steric and electronic properties.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing the cyclobutylamine moiety into more complex molecules via amide coupling, reductive amination, or nucleophilic substitution reactions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring structure-activity relationships (SAR) and new chemical spaces.
• Fine Chemical Production: Integral to the manufacture of high-value, low-volume specialty chemicals used in electronics and material science.

Basic Information

Product Name	Cyclobutylamine Hydrochloride
CAS No.	6291-01-6
Molecular Formula	C4H9N·HCl
Molecular Weight	107.58 g/mol
Synonyms	Cyclobutylammonium chloride; Cyclobutanamine hydrochloride; 1-Cyclobutylamine hydrochloride; Aminocyclobutane hydrochloride; Cyclobutylamine HCl; Cyclobutaneamine hydrochloride; Cyclobutylamine, hydrochloride
EINECS	228-529-5

Quality Control

Our Cyclobutylamine Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and reproducible synthetic results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.