Description

4,6-Dibromo-7H-Dibenzo[De,H]Quinazolin-7-One is a high-purity, halogenated heterocyclic compound that serves as a critical advanced intermediate in organic synthesis. Its value lies in its unique dibrominated quinazolinone structure, which provides versatile reactivity for constructing complex molecular architectures. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for applications requiring the introduction of bromine atoms or the quinazolinone pharmacophore.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its halogenated structure.
• Material Science: Potential precursor for organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to the reactive bromine sites.
• Academic & R&D: Serves as a standard or starting material for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	4,6-Dibromo-7H-Dibenzo[De,H]Quinazolin-7-One
CAS No.	6259-18-3
Molecular Formula	C₁₄H₆Br₂N₂O
Molecular Weight	377.02 g/mol
Synonyms	4,6-Dibromodibenzo[de,h]quinazolin-7(7H)-one; 4,6-Dibromodibenzo[de,h]quinazolin-7-one; 7H-Dibenzo[de,h]quinazolin-7-one, 4,6-dibromo-; Dibenzo[de,h]quinazolin-7(7H)-one, 4,6-dibromo-; 4,6-Dibromo-7H-dibenzo[de,h]quinazolin-7-one; CAS 6259-18-3
EINECS	Contact for details

Quality Control

Our 4,6-Dibromo-7H-Dibenzo[De,H]Quinazolin-7-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.