Description

o-Chloro-Alpha,α-Dimethylphenethyl Alcohol CAS NO 6256-31-1 is a versatile chlorinated aromatic alcohol derivative, serving as a critical chiral intermediate in advanced organic synthesis. Its value lies in the unique steric and electronic properties conferred by the ortho-chloro and gem-dimethyl substituents, which are essential for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the production of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where its structural motif contributes to biological activity and selectivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Intermediate for dyes, pigments, and other performance chemicals requiring specific aromatic substitution patterns.
• Academic and Industrial Research: Valuable reference standard and starting material for methodological development in organic chemistry.

Basic Information

Product Name	o-Chloro-Alpha,α-Dimethylphenethyl Alcohol
CAS No.	6256-31-1
Molecular Formula	C10H13ClO
Molecular Weight	184.66 g/mol
Synonyms	2-Chloro-α,α-dimethylbenzeneethanol; 1-(2-Chlorophenyl)-2-methylpropan-2-ol; o-Chloro-α,α-dimethylphenethyl alcohol; 2-Chloro-α,α-dimethylphenethyl alcohol; (2-Chlorophenyl)-2-methyl-2-propanol; Benzenemethanol, 2-chloro-α,α-dimethyl-; α-(2-Chlorophenyl)-2-methyl-2-propanol
EINECS	228-402-6

Quality Control

Our o-Chloro-Alpha,α-Dimethylphenethyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.