Description

3-Aminomethyl-Oxetane is a versatile heterocyclic building block featuring a reactive oxetane ring and a primary amine functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing advanced polymers, pharmaceutical compounds, and specialty chemicals. It is particularly sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and polymer industries for introducing both rigidity and amine functionality into target molecules.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing the oxetane moiety to improve metabolic stability and solubility.
• Polymer & Resin Modifier: Serves as a monomer or cross-linking agent for producing high-performance polyamides, epoxy resins, and polyurethanes with enhanced thermal and mechanical properties.
• Agrochemical Synthesis: A key building block for creating new herbicides, fungicides, and insecticides with optimized efficacy and environmental profiles.
• Ligand & Catalyst Preparation: Employed in the development of specialized ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Surface Modification Agent: Used to functionalize surfaces (e.g., silica, polymers) to introduce amine groups for further chemical grafting or to alter surface properties.
• Linker for Bioconjugation: Applied in biotech for creating cleavable linkers in antibody-drug conjugates (ADCs) and other targeted therapeutic agents.

Basic Information

Product Name	3-Aminomethyl-Oxetane
CAS No.	6246-05-5
Molecular Formula	C4H9NO
Molecular Weight	87.12 g/mol
Synonyms	3-(Aminomethyl)oxetane; Oxetan-3-ylmethanamine; 3-Oxetanemethylamine; 3-Aminomethyloxacyclobutane; (Oxetan-3-yl)methanamine; 3-Oxetanylmethylamine; Aminomethyloxetane; 3-AMO
EINECS	228-378-5

Quality Control

Our 3-Aminomethyl-Oxetane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its hygroscopic and easily oxidized nature, containers should be kept sealed and allowed to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.